Cells that double their entire genome do not all share the same fate. New research published in the Proceedings of the ...
Scientists have uncovered a surprising twist in how cells behave when division goes wrong. Sometimes a cell successfully copies its DNA but fails to split into two, leaving it with double the genetic ...
Chromatin bridges are strands of incompletely segregated DNA connecting the anaphase poles or daughter nuclei. If unresolved, chromatin bridges can break in cytokinesis leading to micronuclei ...
In animal cells, mitotic cell division involves a highly coordinated series of events that lead to the formation of two daughter cells. It has been observed in many types of cells that actin and ...
Cytokinesis is the physical separation of two cells that occurs after the completion of mitosis. The mechanism underlying it is very complex. Until recently, the processes that lead to cleavage furrow ...
How does the cell organize multi-step cytokinetic processes to successfully separate cells after division? The final step in cell division is cytokinesis, where the cytoplasm divides into two after ...
Cells that acquire a doubled genome after a failed division step survive and proliferate far more effectively than cells left ...
As cell biologists, Université de Montréal professor Greg FitzHarris and his Ph.D. student Lia Paim are very interested in fertility and what happens inside the eggs and embryos of the mice they study ...