Misfolded proteins cause intracellular stress, which induces the unfolded-protein response (UPR). The UPR is a three-pronged signalling pathway that induces genes which cause cells to acquire a ...
The endoplasmic reticulum (ER) is a crucial intracellular organelle that is involved in the biosynthesis of cellular molecules, including proteins, carbohydrates and lipids. These become constituents ...