The prevalence of obesity is steadily rising and has huge health and financial implications for society. Weight gain is due to an imbalance between dietary intake and energy expenditure and research ...

Obesity associated with hypothalamic dysfunction was initially described in patients with craniopharyngioma. Hypothalamic obesity may also result from brain radiation, infection (eg, tuberculosis), ...

Please provide your email address to receive an email when new articles are posted on . Setmelanotide was linked to reduction in BMI at 52 weeks compared with placebo for patients with acquired ...

Findings showed patients on setmelanotide saw a mean BMI reduction of 16.5% from baseline compared with a 3.3% increase for those on placebo at week 52. Topline data were announced from a phase 3 ...

Hypothalamic obesity (HyOb) is a rare type of obesity caused by damage to the hypothalamus, the brain region that regulates hunger, metabolism, and energy balance. This damage disrupts your body’s ...

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus. In 2022, ...

Please provide your email address to receive an email when new articles are posted on . One-third of a cohort of women with hypothalamic hypogonadism met Rotterdam criteria for polycystic ovary ...

The hypothalamus is the region of the brain that helps to regulate internal conditions like body temperature and blood concentration, but new research shows that it may fail us as we age. The research ...

The Food and Drug Administration (FDA) has extended the review period for setmelanotide in the treatment of acquired hypothalamic obesity. Setmelanotide, a melanocortin-4 receptor agonist, is ...