Oral MYC condensate modulator drives tumor regression and stasis in preclinical modelsDisruption of MYC condensates enables targeted inhibition ...
Efforts to develop effective therapies for MYC-amplified Group 3 medulloblastoma (G3-MB) are hindered by an incomplete ...
Newfindingbuildsuponpreviousconfirmationofmisetionamide’sdirectinhibition of NFkB Directtargetingofthesetwotranscriptionfactorsinhibitsmultipledownstream signaling ...
The Myc family of transcription factors, including Myc, N-Myc, and L-Myc, bind DNA at specific sequences and regulate gene expression by binding to enhancer-box (E-Box) sequences via dimerization with ...
In a recent study published in the Journal of the American Chemical Society, researchers present the second-generation NTB bicyclic stereodiversified peptide library. Study: MYC-Targeting Inhibitors ...
MYC is a transcription factor that plays relevant roles in cellular processes such as glycolysis, development, cell differentiation or proliferation. Recent research has associated the transcriptional ...
Mapping transcription factor (TF) binding sites across the genome is key to understanding how cells control gene expression, yet pinpointing their footprints across the genome—especially in single ...
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