CAR-modified stem cell memory T cells show greater expansion and persistence than standard CAR T cells, enabling complete ...

Scientists analyzing human and mouse pancreatic lymph nodes (PLNs) and spleens have identified a distinct subset of CD4 memory helper T cells associated with type 1 diabetes (T1D). Reported by ...

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and ...

A first-in-human trial from the Leibniz Institute for Immunotherapy found that a low-dose, stem cell memory–enriched CAR T-cell therapy achieved complete remission in some high-risk B-cell cancer ...

A bone marrow transplant can buy time for people with aggressive B-cell cancers. Too often, it does not buy enough. For ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

During vaccination, the immune system is purposefully exposed to weakened, inactivated, or a component of pathogens so that the body can recognize their molecular structures in the future and mount a ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...