The TWEAK/Fn14 signalling pathway is a pivotal regulator of tissue homeostasis, with a dual role in mediating both repair and pathological inflammation. TWEAK, a cytokine of the tumour necrosis factor ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns. Scientists at St. Jude Children's ...

New research has identified a protein that could serve as both a biomarker and therapeutic target to weaken stem-like cancer ...

Alzheimer’s disease (AD) is a serious neurodegenerative disease largely affecting older adults. Apart from age, it also shows sex-based differences, with women being more at risk. However, the origin ...

Both the skin and the lungs function as barrier organs that are continuously exposed to the external environment. Disruption of epithelial or epidermal ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching effects regarding immune responses, inflammatory processes, and diseases. A ...

William “Matt” Howe and Read Montague are senior authors of a study published in Nature Communications that identified a neurochemical signature distinguishing Parkinson’s disease from essential ...

Understanding how muscle deteriorates could help researchers extend the human health span. “When you ask most older adults ...

Identifying lipid-linked genetic pathways in Asian Indians offers insights into diabetes and heart disease, crucial for ...

For nearly three decades, the Liu Lab has contributed foundational discoveries across multiple areas of cell biology, signaling, and disease mechanisms. This work helped define core principles of ...

Plant molecular biology and crop genetics have made significant advances in understanding the mechanisms by which crops respond to biotic stress, such as ...