The signaling pathways of TC21-mediated transformation and cell survival are not well-established. In this study, we have investigated the role of PI3-K/Akt signaling pathway in ...
The Nf1 gene product neurofibromin is a GTPase activating protein (GAP) for Ras proteins. Neurofibromin negatively regulates Ras activity by accelerating the conversion of Ras-GTP to Ras-GDP ...
A phase II clinical trial of drug withdrawal in women with progressive breast cancer while on aromatase inhibitor therapy. Background: Several molecular factors have been associated with the ...
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